DSIP 10vials/box

1. Deep Sleep Promotion (Core Function)

Significantly increases the duration of **slow-wave sleep (delta wave/deep sleep)**, shortens sleep latency, and improves sleep efficiency.

Does not inhibit REM sleep, does not alter normal sleep structure, and leaves no hangover upon waking.

Clinical studies: A single intravenous dose can increase total sleep time by 59% in healthy individuals and significantly improve sleep efficiency in those with chronic insomnia.

Suitable for: Insomnia, fragmented sleep, jet lag, shift work, and sleep apnea.

2. Stress and Cortisol Regulation

Inhibits ACTH (adrenocorticotropic hormone) release, reducing basal and stress-induced cortisol levels.

Regulates the HPA axis, breaking the vicious cycle of "high cortisol → insomnia → even higher cortisol".

Symptoms: Relieves anxiety, tension, stress headaches, and PTSD-related sleep disorders.

3. Analgesia and Neuroprotection

Activates the endogenous opioid system, reducing pain perception in a receptor-independent manner.

Relieves chronic pain, postoperative/injury pain, and migraines.

Antioxidant and anti-neuroinflammatory, protects neurons, and improves damage in models of cerebral ischemia/neurodegenerative disorders.

Improves brain fog, attention, memory, and cognitive function.

4. Hormonal and Metabolic Regulation

Promotes **growth hormone (GH)** secretion (GH peak during deep sleep), aiding in repair, anti-aging, and optimizing body composition.

Regulates melatonin secretion, stabilizing circadian rhythms.

Assists in blood pressure regulation, immune support, and postoperative/exercise recovery.

5. Other Research Directions

Animal experiments show: reduced spontaneous tumor incidence, extended maximum lifespan, chromosome protection, and delayed reproductive aging.

Mitochondrial protection, free radical scavenging, and improved metabolic and energy status.

II. Mechanism of Action (Core Pathways)

Neurotransmitters: Regulates GABA, serotonin, and norepinephrine, balancing excitation and inhibition.

Endocrine: Inhibits ACTH/cortisol, promotes GH and melatonin, and regulates the HPA axis.

Neuroprotective effects: Antioxidant, anti-apoptotic, anti-inflammatory, supports mitochondrial function.

III. Safety and Characteristics: No risk of dependence, tolerance, hangover, or REM suppression as associated with traditional sleeping pills.

Common mild reactions: Daytime sleepiness (due to inappropriate dosage/timing), mild headache, transient hypotension (rare).

Mostly administered subcutaneously (30-60 minutes before bedtime). Commonly used study dose: 100-300 mcg/dose, 5 days a week, 8-12 weeks per cycle.

IV. Target Population (Research Level):

Chronic insomnia, poor sleep quality, frequent awakenings, early awakenings; High stress, anxiety, cortisol disorders, jet lag/shift work; Chronic pain, post-operative/sports recovery, nervous fatigue; Individuals needing cognitive improvement, anti-aging, or hormonal balance.