CJC 1295 (with DAC) 10vials/box

Basic Information

Full Name: CJC-1295 with DAC (with drug affinity complex), also known as CJC-1295 DAC

CAS: 863288-35-1

Structure: 29-amino acid GHRH analog (same as the DAC-free version), covalently coupled with DAC (drug affinity complex), can bind to serum albumin

Appearance: White lyophilized powder, good water solubility

II. Core Mechanism of Action (Substantial Difference from the DAC-Free Version)

Long-lasting and sustained increase in GH/IGF-1

DAC covalently binds to serum albumin, avoiding renal clearance and enzymatic degradation, extending the half-life from 30 minutes to 6-8 days.

Single injection continuously activates pituitary GHRH receptors, continuously releasing GH, and steadily increasing IGF-1 (single injection can maintain this for 11 days).

Non-pulsatile, continuous anabolic metabolism

Disrupts the natural GH pulsatile rhythm, 24 Continuous anabolism signaling, suitable for long-term muscle building, repair, and anti-aging.

Disadvantages: May cause pituitary desensitization, negative feedback inhibition, and persistently high IGF-1 levels.

Downstream effects: Strong muscle building, fat loss, tissue repair, skin anti-aging, and increased bone density.

III. Core Efficacy (Research/Application)

1. Continuous Anabolism (Strongest): Continuously increases IGF-1, powerfully building muscle, reducing body fat, and preserving muscle mass.

Improves strength, endurance, and athletic performance.

2. Long-Term Injury Repair: Accelerates the repair of chronic injuries to tendons/ligaments, joints, and muscles.

Suitable for post-operative recovery, long-term strain, and sports injury recovery.

3. Anti-aging and Metabolic Optimization: Improves skin elasticity, reduces wrinkles, and improves sleep quality.

Mildly improves insulin sensitivity, blood lipids, and bone density.