Semax 10vials/box

Basic Information

Full Name / Aliases: Semax, Semak, ACTH (4-10) Analog, Nootropic Heptapeptide, Neuroprotective Heptapeptide

Sequence: Met-Glu-His-Phe-Pro-Gly-Pro (MEHFPGP)

CAS: 80714-61-0

Dosage Form: In Russia, it is available as nasal drops/nasal spray (0.1% blue box, 1% red box); in the research market, it is mostly available as lyophilized powder (5mg/bottle)

II. Core Functions and Mechanisms (Stronger than Selank in Neural Repair)

1. Powerful Cognitive Enhancement (Core)

Significantly upregulates BDNF (brain-derived neurotrophic factor): A single dose can increase BDNF protein in the hippocampus by 40% and mRNA by 3 times, directly enhancing synaptic plasticity, learning and memory, and attention.

Regulates dopamine, 5- 1. **Serotonin and acetylcholine system:** Enhances focus, thinking speed, and combats fatigue.

2. **Inhibits endorphinase, prolonging the effects of endogenous opioid peptides, aiding in mood stabilization and stress resistance.

2. **Neuroprotection (Exclusive Advantage):** Inhibits neuronal apoptosis, reduces oxidative stress, and has anti-inflammatory effects; used for the repair of stroke, traumatic brain injury, optic nerve atrophy, and neurodegenerative diseases.

3. **Activates MAPK/ERK and PI3K/Akt pathways, promoting nerve regeneration and vascular repair.

3. **No Hormonal Side Effects:** Derived from ACTH (4-10), but completely does not stimulate cortisol secretion, has no HPA axis interference, and is not adrenal dependent.

**Reconstitution:** Lyophilized powder dissolved in **antibacterial water (BAC Water)**, stored at 2-8℃.